{"id":46942,"date":"2023-01-13T05:05:51","date_gmt":"2023-01-13T05:05:51","guid":{"rendered":"http:\/\/timessouthafrica.com\/?guid=ae31033808854f09dc3ad9a8faf43cb0"},"modified":"2023-01-13T05:05:51","modified_gmt":"2023-01-13T05:05:51","slug":"sabin-vaccine-institute-recebe-us-35-milhoes-da-barda-com-potencial-de-ate-us-214-milhoes-para-a-fabricacao-de-vacinas-ebola-sudao-e-marburg","status":"publish","type":"post","link":"https:\/\/timessouthafrica.com\/sabin-vaccine-institute-recebe-us-35-milhoes-da-barda-com-potencial-de-ate-us-214-milhoes-para-a-fabricacao-de-vacinas-ebola-sudao-e-marburg\/","title":{"rendered":"Sabin Vaccine Institute recebe US $ 35 milh\u00f5es da BARDA com potencial de at\u00e9 US $ 214 milh\u00f5es para a fabrica\u00e7\u00e3o de vacinas Ebola Sud\u00e3o e Marburg"},"content":{"rendered":"
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Sabin Vaccine Institute fecha contrato com a BARDA com potencial de financiamento de at\u00e9 US $ 214 milh\u00f5es para fabrica\u00e7\u00e3o de vacinas contra Ebola Sud\u00e3o e Marburg<\/h5>\n<\/div>\n
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O Sabin Vaccine Institute ir\u00e1 produzir at\u00e9 100.000 doses da vacina Sabin Ebola Sud\u00e3o como parte de um novo contrato plurianual com a BARDA<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

WASHINGTON, Jan. 12, 2023 (GLOBE NEWSWIRE) — O Sabin Vaccine Institute anunciou hoje que a Biomedical Advanced Research and Development Authority (BARDA) fechou com a Sabin um contrato plurianual com potencial de financiamento de at\u00e9 US $ 214 milh\u00f5es para o avan\u00e7o do desenvolvimento e da produ\u00e7\u00e3o de vacinas candidatas \u00e0 dose \u00fanica para as doen\u00e7as causadas pelos v\u00edrus Ebola Sud\u00e3o e Marburg.<\/p>\n

Atualmente n\u00e3o existem vacinas licenciadas contra os v\u00edrus Ebola Sud\u00e3o e Marburg, que causam febre hemorr\u00e1gica e matam aproximadamente metade das pessoas infectadas.<\/p>\n

A BARDA, parte da Administra\u00e7\u00e3o de Prepara\u00e7\u00e3o e Resposta Estrat\u00e9gica (ASPR) do Departamento de Sa\u00fade e Servi\u00e7os Humanos dos EUA, investir\u00e1 inicialmente aproximadamente US $ 35 milh\u00f5es para produzir at\u00e9 100.000 doses da vacina da Sabin contra o v\u00edrus Ebola Sud\u00e3o (ChAd3-SUDV). Essas vacinas podem ser usadas como parte dos esfor\u00e7os cont\u00ednuos de prepara\u00e7\u00e3o dos EUA e em resposta a futuros surtos globais.<\/p>\n

A vacina Sabin foi a primeira a chegar a Uganda durante o recente surto do v\u00edrus Ebola no Sud\u00e3o que causou 55 mortes, depois que a Organiza\u00e7\u00e3o Mundial de Sa\u00fade a incluiu como uma das tr\u00eas vacinas para poss\u00edvel uso em um teste de surto em Uganda.<\/a> O pa\u00eds declarou que o surto de Ebola no Sud\u00e3o havia terminado em 11 de janeiro<\/a>, quatro meses ap\u00f3s o primeiro caso confirmado.<\/p>\n

\u201cA Sabin entregou com sucesso a Uganda doses da vacina contra o Ebola Sud\u00e3o em 79 dias depois do in\u00edcio do surto \u2013 uma conquista impressionante\u201d, disse a Diretora Executiva da Sabin, Amy Finan. \u201cEste novo contrato permite que a Sabin produza at\u00e9 100.000 doses para que o mundo esteja preparado com anteced\u00eancia para futuros surtos.\u201d<\/p>\n

Al\u00e9m de participar de atividades recentes de surto, a Sabin continua seu plano de desenvolvimento no Sud\u00e3o e iniciou a Fase 2 de planejamento de ensaios cl\u00ednicos em Uganda e no Qu\u00eania. Com base em ensaios cl\u00ednicos anteriores, a vacina contra o Ebola Sud\u00e3o da Sabin \u00e9 segura e imunog\u00eanica, e em estudos com primatas n\u00e3o humanos demonstrou prote\u00e7\u00e3o r\u00e1pida, durabilidade de at\u00e9 12 meses e efic\u00e1cia.<\/p>\n

Al\u00e9m da vacina ChAd3-SUDV da Sabin, o contrato tamb\u00e9m inclui suporte para a fabrica\u00e7\u00e3o da vacina da Sabin contra o v\u00edrus Marburg (ChAd3-MARV), que podem gerar doses que podem ser usadas em testes e em resposta a um poss\u00edvel surto do v\u00edrus Marburg. Em Julho passado, duas pessoas em Gana morreram depois de terem sido infectadas com o v\u00edrus Marburg<\/a>, e isso demonstra claramente a necessidade urgente da cria\u00e7\u00e3o de vacinas.<\/p>\n

O novo contrato alavanca uma parceria com a BARDA que teve in\u00edcio em 2019, quando a ag\u00eancia fechou com a Sabin outro contrato de v\u00e1rios anos com um valor de US $ 128 milh\u00f5es para o desenvolvimento de vacinas contra os v\u00edrus Marburg e Ebola Sud\u00e3o.<\/p>\n

\u201cA BARDA tem sido parceira de apoio \u00e0s nossas medidas essenciais para a prepara\u00e7\u00e3o para a pandemia\u201d, disse Finan. \u201cO surto de Ebola Sud\u00e3o em Uganda ressaltou a necessidade vital de solu\u00e7\u00f5es prontamente dispon\u00edveis. E teremos amplo material para responder rapidamente a esse surto no futuro.\u201d<\/p>\n

Este projeto ser\u00e1 financiado, no todo, com fundos federais do Departamento de Sa\u00fade e Servi\u00e7os Humanos; Administra\u00e7\u00e3o para Prepara\u00e7\u00e3o e Resposta Estrat\u00e9gica; Autoridade de Pesquisa e Desenvolvimento Avan\u00e7ado Biom\u00e9dico, sob o contrato n\u00famero 75A50123C00010.<\/p>\n

Sobre o Sabin Vaccine Institute<\/strong><\/p>\n

O Sabin Vaccine Institute \u00e9 um dos principais defensores da expans\u00e3o do acesso e uso de vacinas em todo o mundo, do avan\u00e7o da pesquisa e desenvolvimento de vacinas e da amplia\u00e7\u00e3o do conhecimento e inova\u00e7\u00e3o das vacinas. Revelando o potencial das vacinas atrav\u00e9s da parceria, o Sabin criou um ecossistema robusto de financiadores, inovadores, implementadores, profissionais, formuladores de pol\u00edticas e partes interessadas p\u00fablicas para avan\u00e7ar sua vis\u00e3o de um futuro livre de doen\u00e7as evit\u00e1veis. Como uma organiza\u00e7\u00e3o sem fins lucrativos com tr\u00eas d\u00e9cadas de experi\u00eancia, o Sabin est\u00e1 empenhado em encontrar solu\u00e7\u00f5es duradouras que levem todos os benef\u00edcios das vacinas a todas as pessoas, independentemente de quem sejam ou de onde vivem. No Sabin, acreditamos no poder das vacinas para mudar o mundo. Para mais informa\u00e7\u00e3o, visite\u00a0www.sabin.org<\/a> e siga-nos no Twitter,\u00a0@SabinVaccine<\/a>.<\/p>\n

Sobre a Ebola Sud\u00e3o e Marburg<\/strong><\/p>\n

Ebola Sud\u00e3o e Marburg s\u00e3o membros da fam\u00edlia dos filov\u00edrus. Ambos podem causar febre hemorr\u00e1gica grave em seres humanos e primatas n\u00e3o humanos. Nenhum tratamento terap\u00eautico das febres hemorr\u00e1gicas foi licenciado at\u00e9 o momento. Os v\u00edrus Marburg e Ebola s\u00e3o transmitidos aos seres humanos por animais infectados, particularmente pelos morcegos-fruta. Uma vez infectada, uma pessoa pode transmitir o v\u00edrus para outras pessoas atrav\u00e9s do contato pessoal pr\u00f3ximo ou com fluidos corporais. O isolamento das pessoas infectadas atualmente \u00e9 a parte central do controle do filov\u00edrus.<\/p>\n

O Marburg foi o primeiro filov\u00edrus a ser identificado em 1967, quando surtos de febre hemorr\u00e1gica foram relatados em alguns laborat\u00f3rios da Europa, incluindo na cidade de Marburg, Alemanha. A ebola foi identificada em 1976, quando dois surtos simult\u00e2neos ocorreram no norte do Zaire (agora RDC) em uma aldeia perto do rio Ebola e sul do Sud\u00e3o. Os surtos envolveram o que eventualmente provou ser duas esp\u00e9cies diferentes do v\u00edrus Ebola; ambos receberam o nome na\u00e7\u00f5es em que foram descobertos.<\/p>\n

Para Informa\u00e7\u00f5es para a M\u00eddia:<\/strong><\/p>\n

press@sabin.org<\/strong><\/a><\/p>\n

Contato com a M\u00eddia: <\/strong>
\nMonika Guttman
\nEspecialista em Rela\u00e7\u00f5es com a M\u00eddia
\nSabin Vaccine Institute
\n+1 (202) 662-1841
\npress@sabin.org<\/a><\/p>\n

Foto deste comunicado dispon\u00edvel em https:\/\/www.globenewswire.com\/NewsRoom\/AttachmentNg\/539c9127-e5d6-4b32-9e89-780f7461314b\/pt<\/a><\/p>\n

GlobeNewswire Distribution ID 8729001<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Sabin Vaccine Institute fecha contrato com a BARDA com potencial de financiamento de at\u00e9 US $ 214 milh\u00f5es para fabrica\u00e7\u00e3o de vacinas contra Ebola Sud\u00e3o e Marburg WASHINGTON, Jan. 12, 2023 (GLOBE NEWSWIRE) \u2014 O Sabin Vaccine Institute anunciou hoje que a Biomedical Advanced Research and Development Authority (BARDA) fechou com a Sabin um contrato [\u2026]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[10,12],"yoast_head":"\nSabin Vaccine Institute recebe US $ 35 milh\u00f5es da BARDA com potencial de at\u00e9 US $ 214 milh\u00f5es para a fabrica\u00e7\u00e3o de vacinas Ebola Sud\u00e3o e Marburg - Times South Africa<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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